The Ministry has four State Secretariats: the State Secretariat for the European Union, the State Secretariat for International Cooperation, the State Secretariat for Ibero-America and the Caribbean and the State Secretariat for Global Spain.
Fernando Martín Valenzuela Marzo was appointed as State Secretary for Foreign Affairs at the Council of Ministers held on 15 June 2018.
Luis Marco Aguiriano Nalda was appointed as State Secretary for the European Union at the Council of Ministers held on 22 June 2018.
Juan Pablo de Laiglesia y González de Peredo was appointed as State Secretary for International Cooperation and for Ibero-America and the Caribbean at the Council of Ministers on 22 June 2018.
Irene Lozano Domingo was named State Secretary for Global Spain at the Council of Ministers on 11 October 2018.